A Dual-Functional Orphan Response Regulator Negatively Controls the Differential Transcription of Duplicate groEL s and Plays a Global Regulatory Role in Myxococcus

Author:

Zhuo Li1,Wan Tian-yu1,Pan Zhuo1,Wang Jia-ning1,Sheng Duo-hong1ORCID,Li Yue-zhong1ORCID

Affiliation:

1. State Key Laboratory of Microbial Technology, Institute of Microbial Technology, Shandong University, Qingdao, People’s Republic of China

Abstract

Multiply copied groEL s require precise regulation of transcriptions for their divergent cellular functions. Here, we reported that an orphan response regulator (RR) tunes the transcriptional discrepancy of the duplicate groEL s in Myxococcus xanthus DK1622 in a dual-functional mode.

Funder

Special Investigation on Scientific and Technological Basic Resources

Key Research and Development Program of Shandong Province

Qingdao Postdoctoral Application Research Project of China

China Postdoctoral Science Foundation | National Postdoctoral Program for Innovative Talents

MOST | National Key Research and Development Program of China

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modeling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

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