Cellular RNA Targets of Cold Shock Proteins CspC and CspE and Their Importance for Serum Resistance in Septicemic Escherichia coli

Author:

Yair Yael1,Michaux Charlotte2ORCID,Biran Dvora1,Bernhard Jörg3,Vogel Jörg24ORCID,Barquist Lars45ORCID,Ron Eliora Z.1ORCID

Affiliation:

1. The Shmunis School of Biomedicine and Cancer Research, George S. Wise Faculty of Life Sciences, Tel-Aviv University, Tel Aviv, Israel

2. RNA Biology Group, Institute of Molecular Infection Biology, University of Würzburg, Würzburg, Germany

3. Institute for Microbiology, Ernst-Moritz-Arndt-Universität, Greifswald, Germany

4. Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Center for Infection Research (HZI), Würzburg, Germany

5. Faculty of Medicine, University of Würzburg, Würzburg, Germany

Abstract

Virulent Escherichia coli strains that cause infections outside the intestinal tract—extraintestinal pathogenic E. coli (ExPEC)—constitute a major clinical problem worldwide. They are involved in several distinct conditions, including urinary tract infections, newborn meningitis, and sepsis.

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modeling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

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