Incidence of an Intracellular Multiplication Niche among Acinetobacter baumannii Clinical Isolates

Author:

Rubio Tristan1ORCID,Gagné Stéphanie1,Debruyne Charline1,Dias Chloé1ORCID,Cluzel Caroline2,Mongellaz Doriane1,Rousselle Patricia2ORCID,Göttig Stephan3ORCID,Seifert Harald45ORCID,Higgins Paul G.45ORCID,Salcedo Suzana P.1ORCID

Affiliation:

1. Laboratory of Molecular Microbiology and Structural Biochemistry, Centre National de la Recherche Scientifique UMR5086, Université de Lyon, Lyon, France

2. Laboratoire de Biologie Tissulaire et d’Ingénierie Thérapeutique, UMR5305, CNRS, Université de Lyon, France

3. Institute for Medical Microbiology and Infection Control, University Hospital, Goethe University Frankfurt am Main, Frankfurt, Germany

4. Institute for Medical Microbiology, Immunology and Hygiene, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany

5. German Centre for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany

Abstract

Multidrug-resistant Acinetobacter baumannii isolates are associated with significant morbidity and mortality in hospitals worldwide. Understanding their pathogenicity is critical for improving therapeutic management.

Funder

Fondation pour la Recherche Medicale

Deutsche Forschungsgemeinschaft

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modeling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

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