Computationally Efficient Assembly of Pseudomonas aeruginosa Gene Expression Compendia

Author:

Doing Georgia1ORCID,Lee Alexandra J.2ORCID,Neff Samuel L.1,Reiter Taylor3,Holt Jacob D.1,Stanton Bruce A.1,Greene Casey S.34ORCID,Hogan Deborah A.1ORCID

Affiliation:

1. Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA

2. Genomics and Computational Biology Graduate Program, University of Pennsylvania, Philadelphia, Pennsylvania, USA

3. Department of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Denver, Colorado, USA

4. Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA

Abstract

Pseudomonas aeruginosa is a causative agent of a wide range of infections, including chronic infections associated with cystic fibrosis. These P. aeruginosa infections are difficult to treat and often have negative outcomes.

Funder

HHS | NIH | National Institute of General Medical Sciences

Cystic Fibrosis Foundation

HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modeling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

Reference61 articles.

1. Cystic Fibrosis Foundation. 2019. Cystic Fibrosis Foundation patient registry 2019 annual data report. Cystic Fibrosis Foundation, Bethesda, MD.

2. Groundwater, soil and compost, as possible sources of virulent and antibiotic-resistant Pseudomonas aeruginosa

3. Pseudomonas aeruginosa population structure revisited under environmental focus: impact of water quality and phage pressure

4. Isolation of Pseudomonas aeruginosa from Open Ocean and Comparison with Freshwater, Clinical, and Animal Isolates

5. Use of growing cells of Pseudomonas aeruginosa for synthesis of the natural vanillin via conversion of isoeugenol;Ashengroph M;Iran J Pharm Res,2011

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