Global Transcriptional Regulators Fine-Tune the Translational and Metabolic Efficiency for Optimal Growth of Escherichia coli-Reference-Cited by-同舟云学术

Global Transcriptional Regulators Fine-Tune the Translational and Metabolic Efficiency for Optimal Growth of Escherichia coli

Published:2021-04-27 Issue:2 Volume:6 Page:
ISSN:2379-5077
Container-title:mSystems
language:en
Short-container-title:mSystems

Author:

Iyer Mahesh S.¹,Pal Ankita¹,Srinivasan Sumana¹,Somvanshi Pramod R.¹,Venkatesh K. V.¹^ORCID

Affiliation:

1. Department of Chemical Engineering, Indian Institute of Technology Bombay, Mumbai, India

Abstract

Cellular proteome allocation in response to environmental or internal perturbations governs their eventual phenotypic outcome. This entails striking an effective balance between amino acid biosynthesis by metabolic proteins and its consumption by ribosomes.

Funder

Department of Biotechnology, Ministry of Science and Technology, India

Department of Science and Technology, Ministry of Science and Technology, India

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modelling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mSystems.00001-21

Reference81 articles.

1. Quantifying Absolute Protein Synthesis Rates Reveals Principles Underlying Allocation of Cellular Resources

2. Energetics of bacterial growth: balance of anabolic and catabolic reactions

3. Proteome reallocation in Escherichia coli with increasing specific growth rate

4. Emergence of robust growth laws from optimal regulation of ribosome synthesis

5. Growth Rate-Dependent Global Effects on Gene Expression in Bacteria

Cited by 19 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Achieving robust synthetic tolerance in industrial E. coli through negative auto-regulation of a DsrA-Hfq module;Synthetic and Systems Biotechnology;2024-09

2. CemR atypical response regulator impacts energy conversion in Campylobacteria;mSystems;2024-08-20

3. Convergent genetic adaptation of Escherichia coli in minimal media leads to pleiotropic divergence;Frontiers in Molecular Biosciences;2024-04-10

4. CemR atypical response regulator impacts energy conversion inCampylobacteria;2024-03-07

5. Metabolome analysis of metabolic burden in Escherichia coli caused by overexpression of green fluorescent protein and delta-rhodopsin;Journal of Bioscience and Bioengineering;2024-03