Bactericidal Activity and Postantibiotic Effect of Levofloxacin against Anaerobes-Reference-Cited by-同舟云学术

Bactericidal Activity and Postantibiotic Effect of Levofloxacin against Anaerobes

Published:1999-10 Issue:10 Volume:43 Page:2547-2549
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Pendland Susan L.¹²,Diaz-Linares Mariela²,Garey Kevin W.²,Woodward Jennifer G.³,Ryu Seonyoung⁴,Danziger Larry H.¹²

Affiliation:

1. Microbiology Research Laboratory1 and

2. Department of Pharmacy Practice,2 The University of Illinois at Chicago, Chicago, Illinois 60612;

3. Lutheran General Hospital, Park Ridge, Illinois 600683; and

4. Cedars-Sinai Health Systems, Beverly Hills, California 902114

Abstract

ABSTRACT The bactericidal activity and postantibiotic effect (PAE) of levofloxacin against nine anaerobes were determined. Levofloxacin at concentrations of the MIC and twice the MIC was bactericidal at 24 h to five of nine and nine of nine strains, respectively. The PAE of levofloxacin following a 2-h exposure ranged from 0.06 to 2.88 h.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.43.10.2547

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