The Innate Immune Response in the Marmoset during the Acute Pneumonic Disease Caused by Burkholderia pseudomallei-Reference-Cited by-同舟云学术

The Innate Immune Response in the Marmoset during the Acute Pneumonic Disease Caused by Burkholderia pseudomallei

Published:2022-03-17 Issue:3 Volume:90 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Ngugi Sarah¹,Laws Thomas¹,Simpson Andrew J.¹²³,Nelson Michelle¹^ORCID

Affiliation:

1. CBR division, DSTL Porton Down, Salisbury, Wiltshire, United Kingdom

2. Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit (LOMWRU), Mahosot Hospital, Vientiane, Lao People’s Democratic Republic

3. Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom

Abstract

Burkholderia pseudomallei is the causative agent of melioidosis, a severe human infection that is difficult to treat with antibiotics and for which there is no effective vaccine. Development of novel treatments rely upon appropriately characterized animal models.

Funder

HHS | Biomedical Advanced Research and Development Authority

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.00550-21

Reference46 articles.

1. Predicted global distribution of Burkholderia pseudomallei and burden of melioidosis

2. Burkholderia pseudomallei: Challenges for the Clinical Microbiology Laboratory

3. Characterization of a Murine Model of Melioidosis: Comparison of Different Strains of Mice

4. BALB/c and C57Bl/6 mice infected with virulentBurkholderia pseudomalleiprovide contrasting animal models for the acute and chronic forms of human melioidosis

5. Burkholderia pseudomallei aerosol infection results in differential inflammatory responses in BALB/c and C57Bl/6 mice

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