A Molecular Basis for Tungstate Selectivity in Prokaryotic ABC Transport Systems-Reference-Cited by-同舟云学术

A Molecular Basis for Tungstate Selectivity in Prokaryotic ABC Transport Systems

Published:2011-09-15 Issue:18 Volume:193 Page:4999-5001
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Bevers Loes E.¹,Schwarz Guenter²,Hagen Wilfred R.¹

Affiliation:

1. Department of Biotechnology, Delft University of Technology, Delft, Netherlands

2. Institute of Biochemistry, Department of Chemistry and Center for Molecular Medicine, University of Cologne, Zülpicher Str. 47, 50674 Cologne, Germany

Abstract

ABSTRACT The essential trace compounds tungstate and molybdate are taken up by cells via ABC transporters. Despite their similar ionic radii and chemical properties, the WtpA protein selectively binds tungstate in the presence of molybdate. Using site-directed mutagenesis of conserved binding pocket residues, we established a molecular basis for tungstate selectivity.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.05056-11

Reference13 articles.

1. Tungsten, the surprisingly positively acting heavy metal element for prokaryotes;Andreesen J. R.;Ann. N. Y. Acad. Sci,2008

2. The bioinorganic chemistry of tungsten;Bevers L. E.;Coord. Chem. Rev,2009

3. Tungsten Transport Protein A (WtpA) in Pyrococcus furiosus : the First Member of a New Class of Tungstate and Molybdate Transporters

4. Oxyanion Selectivity in sulfate and molybdate transport proteins: an ab initio/CDM study;Dudev T.;J. Am. Chem. Soc,2004

5. Cellular uptake of molybdenum and tungsten;Hagen W. R.;Coord. Chem. Rev,2011

Cited by 9 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Overexpression of a Designed Mutant Oxyanion Binding Protein ModA/WtpA in Acidithiobacillus ferrooxidans for the Low pH Recovery of Molybdenum and Rhenium;JACS Au;2024-07-13

2. Molybdenum enzymes;Metalloenzymes;2024

3. The Development of Tungsten Biochemistry—A Personal Recollection;Molecules;2023-05-11

4. Molybdenum cofactor biology, evolution and deficiency;Biochimica et Biophysica Acta (BBA) - Molecular Cell Research;2021-01

5. Efficient bioaccumulation of tungsten by Escherichia coli cells expressing the Sulfitobacter dubius TupBCA system;Systematic and Applied Microbiology;2019-09