Resistance of Candida albicans biofilms to antifungal agents in vitro-Reference-Cited by-同舟云学术

Resistance of Candida albicans biofilms to antifungal agents in vitro

Published:1995-09 Issue:9 Volume:39 Page:2128-2131
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Hawser S P¹,Douglas L J¹

Affiliation:

1. Laboratory of Microbiology, University of Glasgow, United Kingdom.

Abstract

Biofilms formed by Candida albicans on small discs of catheter material were resistant to the action of five clinically important antifungal agents as determined by [3H]leucine incorporation and tetrazolium reduction assays. Fluconazole showed the greatest activity, and amphotericin B showed the least activity against biofilm cells. These findings were confirmed by scanning electron microscopy of the biofilms.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.39.9.2128

Reference14 articles.

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