Leishmania donovani Lipophosphoglycan Increases Macrophage-Dependent Chemotaxis of CXCR6-Expressing Cells via CXCL16 Induction-Reference-Cited by-同舟云学术

Leishmania donovani Lipophosphoglycan Increases Macrophage-Dependent Chemotaxis of CXCR6-Expressing Cells via CXCL16 Induction

Published:2019-05 Issue:5 Volume:87 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Chaparro Visnu¹^ORCID,Leroux Louis-Philippe¹^ORCID,Zimmermann Aude¹,Jardim Armando²,Johnston Brent³,Descoteaux Albert¹^ORCID,Jaramillo Maritza¹^ORCID

Affiliation:

1. Institut National de la Recherche Scientifique-Institut Armand-Frappier, Laval, Quebec, Canada

2. Institute of Parasitology, McGill University, Sainte-Anne-de-Bellevue, Quebec, Canada

3. Departments of Microbiology and Immunology and Pediatrics, Dalhousie University, Halifax, Nova Scotia, Canada

Abstract

CXCL16 is a multifunctional chemokine that is highly expressed by macrophages and other immune cells in response to bacterial and viral pathogens; however, little is known regarding the role of CXCL16 during parasitic infections. The protozoan parasite Leishmania donovani is the causative agent of visceral leishmaniasis.

Funder

Fonds de Recherche du Québec - Santé

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.00064-19

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