Microbiome Profiles of Ligature-Induced Periodontitis in Nonhuman Primates across the Life Span-Reference-Cited by-同舟云学术

Microbiome Profiles of Ligature-Induced Periodontitis in Nonhuman Primates across the Life Span

Published:2019-06 Issue:6 Volume:87 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Kirakodu Sreenatha¹,Chen Jin²,Gonzalez Martinez Janis³,Gonzalez Octavio A.¹⁴,Ebersole Jeffrey¹^ORCID

Affiliation:

1. Center for Oral Health Research, University of Kentucky College of Dentistry, Lexington, Kentucky, USA

2. Division of Bioinformatics and Computational Biology, University of Kentucky College of Medicine, Lexington, Kentucky, USA

3. Caribbean Primate Research Center, Sebana Seca, Puerto Rico, USA

4. Division of Periodontics, University of Kentucky College of Dentistry, Lexington, Kentucky, USA

Abstract

This investigation compared the microbiomes colonizing teeth during the initiation, progression, and resolution of periodontitis in nonhuman primates ( Macaca mulatta ) at different ages. Subgingival plaque samples were collected at baseline; 0.5, 1, and 3 months following ligature-induced periodontitis; and following naturally occurring disease resolution at 5 months.

Funder

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.00067-19

Reference78 articles.

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3. Primary and secondary prevention of periodontal and peri-implant diseases