Effect of Vitamin E on the Immune Response of Hypoxic and Normal Chickens

Author:

Tengerdy Robert P.1,Heinzerling Rollin H.1,Nockels Cheryl F.1

Affiliation:

1. Department of Microbiology and Department of Avian Science, Colorado State University, Fort Collins, Colorado 80521

Abstract

Chicks and hens raised on a diet enriched with 60 mg of vitamin E per lb. of feed had a significantly increased immune response as measured by the antibody plaque-forming cell test or by hemagglutination. Since the effect was much greater on hypoxic (simulated altitude exposed) chicks, a synergistic effect between hypoxia and vitamin E may be suggested.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference12 articles.

1. The in vivo spleen response to sheep red blood cell in bursectomized, irradiated chickens. Acta;Alm G. V.;Pathol. Microbiol. Scand 78(B),1970

2. Further improvement in the plaque technique for detecting single antibody forming cells;Cunningham A. J.;Immunology,1968

3. Fitch C. D. 1968. Experimental anemia in primates due to vitamin E deficiency p. 501-523. In R. S. Harris I. G. Wool and J. A. Loraine (ed.) Vitamins and hormones vol. 26. Academic Press Inc. New York.

4. Plaque forming in agar by single antibody producing cells;Jerne N. K.;Science,1963

5. True primary response to sheep erythrocytes in germ free, colostrum deprived piglets in vivo and in vitro;Kim Y. B.;Fed. Proc.,1968

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