Author:
Reeves M W,Pine L,Neilands J B,Balows A
Abstract
Growth of Legionella species in a defined medium deficient in iron did not result in the production of phenolic or hydroxamate siderophores which could be detected by chemical or biological assay methods. Growth of a variety of other gram-negative organisms under the same conditions resulted in the production of both hydroxamate and phenolate siderophores. The iron-deficient medium limited growth of the Legionella species more severely than it did the growth of the other gram-negative organisms. We have concluded that Legionella species do not make the commonly recognized siderophores, probably because they are restricted in their growth to those environments in which inorganic iron is readily available or is supplied in a form bound to an unknown carrier.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Reference29 articles.
1. Iron acquisition by Neisseria meningitidis in vitro;Archibald F. S.;Infect. Immun.,1980
2. Colorimetric determination of the components of 3,4-dihydroxyphenylalanine-tyrosine mixtures;Arnow L. E.;J. Biol. Chem.,1937
3. Major sites of metal binding in Bacillus licheniformis walls;Beveridge T. J.;J. Bacteriol.,1982
4. On the estimation of bound hydroxylamine in biological materials;Claky T. Z.;Acta Chem. Scand.,1948
5. Feeley J. C. G. W. Gorman and R. J. Gibson. 1978. Primary isolation media and methods p. 107-117. In G. L. Jones and G. A. Hebert (ed.) Legionnaires: the disease the bacterium and methodology. Centers for Disease Control Atlanta Ga.