Affiliation:
1. Department of Biochemistry, University of California, Berkeley, California 94720
Abstract
The effect of methionine starvation on the motility and behavior of normal and nonchemotactic mutants of
Salmonella typhimurium
was investigated. Methionine starvation eliminates tumbling in the wild type, but fails to do so in an uncoordinated (frequent tumbling) mutant. In the mutant, methionine starvation significantly extends the period of smooth motility that follows a sharp temporal increase of attractant. These results suggest that methionine metabolism is not tightly coupled to the generation of tumbles, but rather is necessary for the return of some tumble-regulating parameter to a steady-state level.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Cited by
96 articles.
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