Multiplex PCR for Rapid and Improved Diagnosis of Bloodstream Infections in Liver Transplant Recipients-Reference-Cited by-同舟云学术

Multiplex PCR for Rapid and Improved Diagnosis of Bloodstream Infections in Liver Transplant Recipients

Published:2012-06 Issue:6 Volume:50 Page:2069-2071
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Rath Peter-Michael¹,Saner Fuat²,Paul Andreas²,Lehmann Nils³,Steinmann Eike⁴,Buer Jan¹,Steinmann Joerg¹

Affiliation:

1. Institute of Medical Microbiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

2. Department of General, Visceral and Transplant Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

3. Institute for Medical Informatics, Biometry and Epidemiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

4. Twincore Center for Experimental and Clinical Infection Research, Department of Experimental Virology, Hannover, Germany

Abstract

ABSTRACT This prospective study evaluated the utility of the SeptiFast (SF) test in detecting 25 clinically important pathogens in 225 blood samples from 170 intensive care unit (ICU) patients with suspected sepsis after liver transplantation (LTX) or after other major abdominal surgery (non-LTX). SF yielded a significantly higher positivity rate in the LTX group (52.3%) than in the non-LTX group (30.5%; P = 0.0009). SF may be a powerful tool for the early diagnosis of bloodstream infections in LTX patients.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.00745-12

Reference19 articles.

1. A multicenter trial to compare blood culture with polymerase chain reaction in severe human sepsis;Bloos F;Intensive Care Med.,2010

2. Incidence and significance of Aspergillus cultures following liver and kidney transplantation;Brown RS;Transplantation,1996

3. Revised definitions of invasive fungal disease from the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group;De Pauw B;Clin. Infect. Dis.,2008

4. Fungal infections after liver transplantation;Kusne S;Transplant. Proc.,1988

5. Multiplex Blood PCR in Combination with Blood Cultures for Improvement of Microbiological Documentation of Infection in Febrile Neutropenia

Cited by 32 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A 29-mRNA host-response classifier identifies bacterial infections following liver transplantation – a pilot study;Langenbeck's Archives of Surgery;2024-06-12

2. Normothermic liver machine perfusion as a dynamic platform for assessment and treatment of organs from septic donors;Journal of Hepatology;2023-02

3. Role of microbiological tests and biomarkers in antibiotic stewardship;Seminars in Perinatology;2020-12

4. Delta-Like Canonical Notch Ligand 1 in Patients Following Liver Transplantation—A Secondary Analysis of a Prospective Cohort Study;Diagnostics;2020-10-31

5. Impacts and Challenges of Advanced Diagnostic Assays for Transplant Infectious Diseases;Principles and Practice of Transplant Infectious Diseases;2019