The Effects of Packaged, but Misguided, Single-Stranded DNA Genomes Are Transmitted to the Outer Surface of the ϕX174 Capsid-Reference-Cited by-同舟云学术

The Effects of Packaged, but Misguided, Single-Stranded DNA Genomes Are Transmitted to the Outer Surface of the ϕX174 Capsid

Published:2021-08-25 Issue:18 Volume:95 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Ogunbunmi Elizabeth T.¹,Roznowski Aaron P.¹,Fane Bentley A.¹^ORCID

Affiliation:

1. The BIO5 Institute, University of Arizona, Tucson, Arizona, USA

Abstract

ssDNA viruses utilize icosahedrally ordered protein-nucleic acids interactions to guide and organize their genomes into preformed shells. As previously demonstrated, chaotic genome-capsid associations can inhibit ϕX174 packaging by destabilizing packaging complexes.

Funder

National Science Foundation

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.00883-21

Reference38 articles.

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5. DNA helicase-mediated packaging of adeno-associated virus type 2 genomes into preformed capsids

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