Anticytomegalovirus (Anti-CMV) Immunoglobulin G Avidity in Identification of Pregnant Women at Risk of Transmitting Congenital CMV Infection

Author:

Lazzarotto Tiziana1,Spezzacatena Patrizia1,Varani Stefania1,Gabrielli Liliana1,Pradelli Paola1,Guerra Brunella2,Landini Maria Paola1

Affiliation:

1. Department of Clinical and Experimental Medicine, Section of Microbiology1 and

2. Second Department of Obstetrics and Gynecology,2 Medical School, University of Bologna, Bologna, Italy

Abstract

ABSTRACT In this work, we show that the determination of the anticytomegalovirus antibody avidity carried out before week 18 of gestation is a helpful tool to identify women for enrollment in prenatal diagnosis. This procedure can identify all pregnant women who will give birth to an infected newborn.

Publisher

American Society for Microbiology

Subject

Microbiology (medical),Clinical Biochemistry,Immunology,Immunology and Allergy

Reference18 articles.

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3. Britt W. J. Alford C. A. Cytomegalovirus Fields Virology 3rd ed. Fields B. N. Knipe D. M. Howley P. M. 1996 2493 2523 Lippincott-Raven Publishers Philadelphia Pa

4. Accuracy of amniotic fluid testing before 21 weeks’ gestation in prenatal diagnosis of congenital cytomegalovirus infection.;Donner C.;Prenatal. Diagn.,1994

5. The outcome of congenital cytomegalovirus in relation to maternal antibody status.;Fowler K. B.;N. Engl. J. Med.,1992

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