Detection of RNA of Mumps Virus during an Outbreak in a Population with a High Level of Measles, Mumps, and Rubella Vaccine Coverage

Author:

Bitsko Rebecca H.12,Cortese Margaret M.3,Dayan Gustavo H.3,Rota Paul A.3,Lowe Luis3,Iversen Susan C.4,Bellini William J.3

Affiliation:

1. Epidemic Intelligence Service, Office of Workforce and Career Development

2. National Center on Birth Defects and Developmental Disabilities

3. National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia

4. Student Health Services, University of Kansas, Lawrence, Kansas

Abstract

ABSTRACT The duration of mumps virus RNA detection was studied during a mumps outbreak in a highly vaccinated university population. Seven of the eight reverse transcription-PCR-positive specimens were collected during the first 3 days of parotitis, suggesting that viral shedding is minimal after the first 3 days of symptoms.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference13 articles.

1. American Academy of Pediatrics. 2006. Mumps, p. 464-468. In L. K. Pickering (ed.), Red book: 2006 report of the Committee on Infectious Diseases, 26th ed. American Academy of Pediatrics, Elk Grove Village, IL.

2. Real-Time Reverse Transcription-PCR Assay for Detection of Mumps Virus RNA in Clinical Specimens

3. Centers for Disease Control and Prevention. 2006. Brief report: update: mumps activity—United States, January 1-October 7, 2006. MMWR Morb. Mortal. Wkly. Rep.55:1152-1153.

4. Cusi, M. G., S. Bianchi, M. Valassina, L. Santini, M. Arnetoli, and P. E. Valensin. 1996. Rapid detection and typing of circulating mumps virus by reverse transcription/polymerase chain reaction. Res. Virol.147:227-232.

5. Gupta, R. K., J. Best, and E. MacMahon. 2005. Mumps and the UK epidemic 2005. BMJ330:1132-1135.

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