Antimicrobial Susceptibility and Macrolide Resistance Inducibility of Streptococcus pneumoniae Carrying erm (A), erm (B), or mef (A)-Reference-Cited by-同舟云学术

Antimicrobial Susceptibility and Macrolide Resistance Inducibility of Streptococcus pneumoniae Carrying erm (A), erm (B), or mef (A)

Published:2003-08 Issue:8 Volume:47 Page:2699-2702
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Syrogiannopoulos George A.¹,Grivea Ioanna N.¹,Ednie Lois M.²,Bozdogan Bülent²,Katopodis George D.¹,Beratis Nicholas G.¹,Davies Todd A.²,Appelbaum Peter C.²

Affiliation:

1. Department of Pediatrics, General University Hospital, University of Patras, School of Medicine, Patras, Greece

2. Department of Pathology, The Milton S. Hershey Medical Center, Hershey, Pennsylvania

Abstract

ABSTRACT Erythromycin-resistant Streptococcus pneumoniae isolates from young carriers were tested for their antimicrobial susceptibility; additionally, inducibility of macrolide and clindamycin resistance was investigated in pneumococci carrying erm (A), erm (B), or mef (A). Of 125 strains tested, 101 (81%) were multidrug resistant. Different levels of induction were observed with erythromycin, miocamycin, and clindamycin in erm (B) strains; however, in erm (A) strains only erythromycin was an inducer. Induction did not affect macrolide MICs in mef (A) strains.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.47.8.2699-2702.2003

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