In Vitro Susceptibilities of Seven Leptospira Species to Traditional and Newer Antibiotics-Reference-Cited by-同舟云学术

In Vitro Susceptibilities of Seven Leptospira Species to Traditional and Newer Antibiotics

Published:2003-08 Issue:8 Volume:47 Page:2646-2648
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Hospenthal Duane R.¹,Murray Clinton K.¹

Affiliation:

1. Infectious Disease Service, Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, Texas

Abstract

ABSTRACT Human leptospirosis is generally treated with penicillin or doxycycline. We studied the susceptibilities of 11 serovars (seven species) of Leptospira to 14 antibiotics. With the exception of chloramphenicol, all tested agents were at least as potent as penicillin and doxycycline, with the macrolide and ketolide drugs producing the lowest MICs (and minimal bactericidal concentrations).

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.47.8.2646-2648.2003

Reference14 articles.

1. Penicillins, cephalosporins, and tetracyclines in treatment of hamsters with fatal leptospirosis

2. Alt, D. P., and C. A. Bolin. 1996. Preliminary evaluation of antimicrobial agents for treatment of Leptospira interrogans serovar pomona infection in hamsters and swine. Am. J. Vet. Res.57:59-62.

3. Broughton, E. S., and L. E. Flack. 1986. The susceptibility of a strain of Leptospira interrogans serogroup icterohaemorrhagiae to amoxycillin, erythromycin, lincomycin, tetracycline, oxytetracycline and minocycline. Zentralbl. Bakteriol. Mikrobiol. Hyg. A261:425-431.

4. Edwards, C. N., G. D. Nicholson, T. A. Hassell, C. O. R. Everard, and J. Callender. 1988. Penicillin therapy in icteric leptospirosis. Am. J. Trop. Med. Hyg.39:388-390.

5. Ko, A. I., M. G. Reis, C. M. R. Dourado, W. D. Johnson, L. W. Riley, and the Salvador Leptospirosis Study Group. 1999. Urban epidemic of severe leptospirosis in Brazil. Lancet354:820-825.

Cited by 55 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Current treatment options for leptospirosis: a mini-review;Frontiers in Microbiology;2024-04-25

2. Detection of Antimicrobial Resistance in Veterinary Bacterial Pathogens;Handbook on Antimicrobial Resistance;2023

3. Detection of Antimicrobial Resistance in Veterinary Bacterial Pathogens;Handbook on Antimicrobial Resistance;2023

4. Recent Progress in the Treatment of Leptospirosis;SN Comprehensive Clinical Medicine;2021-02-27

5. Bacteriostatic and Bactericidal Effect of Tigecycline on Leptospira spp.;Antibiotics;2020-07-30