Author:
Gould E A,Allan G M,Logan E F,McFerran J B
Abstract
Batches of commercial fetal bovine serum, described by the suppliers as antibody-free, all contained antibody to bovine syncytial virus (BSV) when tested by indirect immunofluorescence. Antibody to bovine respiratory syncytial virus (RSV) was not detected in these sera. Twenty-four percent of individual fetal bovine sera contained antibody to BSV, and 14% contained antibody to RSV when tested by indirect immunofluorescence. BSV antibody titers in fetal sera from dams with high BSV antibody levels were variable but always higher than RSV antibody titers. Radial immunodiffusion studies with BSV-positive sera revealed the presence of immunoglobulin M (IgM), IgG, and IgA, but the quantity of these immunoglobulins was not directly related to the BSV antibody titers. The evidence suggests that the antibody present in fetal sera arose as the result of infection rather than from maternal transfer across the placenta.
Publisher
American Society for Microbiology
Reference19 articles.
1. Brambell F. R. 1970. The transmission of passive unmunity from mother to young. American Elsevier Publishing Co. New York.
2. The isolation of a strain of bovine syncytial virus in Northern;Clarke J. K.;Ireland. Res. Vet. Sci.,1973
3. Bovine viral diarrhea virus: neutralizing antibodies in a calf obtained by cesarean section from a cow which was infected;Classick L. G.;Am. J. Vet. Res.,1970
4. The morphogenesis and classification of bovine syncytial virus;Dermott E.;J. Gen. Virol.,1971
5. Quantitative determination of serum immunoglobulin in antibodyagar plates;Fahey J. L.;J. Immunol.,1964
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