Stable Recombinant-Gene Expression from a Ligilactobacillus Live Bacterial Vector via Chromosomal Integration-Reference-Cited by-同舟云学术

Stable Recombinant-Gene Expression from a Ligilactobacillus Live Bacterial Vector via Chromosomal Integration

Published:2021-05-11 Issue:11 Volume:87 Page:
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Vezina Ben¹²³⁴^ORCID,Allnutt Theo²⁵,Keyburn Anthony L.²³,Wade Ben¹²⁴,Van Thi Thu Hao⁴^ORCID,Johanesen Priscilla¹²,Lyras Dena¹²^ORCID,Moore Robert J.¹²³⁴^ORCID

Affiliation:

1. Infection and Immunity Program, Monash Biomedicine Discovery Institute, and Department of Microbiology, Monash University, Clayton, Victoria, Australia

2. CSIRO Biosecurity Flagship, Australian Animal Health Laboratory, Geelong, Victoria, Australia

3. Poultry Cooperative Research Center, University of New England, Armidale, NSW, Australia

4. School of Science, RMIT University, Bundoora, Victoria, Australia

5. Theo Allnutt Bioinformatics, Geelong, Victoria, Australia

Abstract

Therapeutic proteins such as antigens can be used to prevent infectious diseases in poultry. However, traditional vaccine delivery by intramuscular or subcutaneous injection generally has not proven effective for mucosa-dwelling microorganisms that live within the gastrointestinal tract.

Funder

Poultry Cooperative Research Centre

Australian Government

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/AEM.00392-21

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