The Peptidoglycan Hydrolase of Staphylococcus aureus Bacteriophage ϕ11 Plays a Structural Role in the Viral Particle-Reference-Cited by-同舟云学术

The Peptidoglycan Hydrolase of Staphylococcus aureus Bacteriophage ϕ11 Plays a Structural Role in the Viral Particle

Published:2013-07-26 Issue:19 Volume:79 Page:6187-6190
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl. Environ. Microbiol.

Author:

Rodríguez-Rubio Lorena,Quiles-Puchalt Nuria,Martínez Beatriz,Rodríguez Ana,Penadés José R.,García Pilar

Abstract

ABSTRACTThe role of virion-associated peptidoglycan hydrolases (VAPGHs) in the phage infection cycle is not clear. gp49, the VAPGH fromStaphylococcus aureusphage ϕ11, is not essential for phage growth but stabilizes the viral particles. ϕ11Δ49 phages showed a reduced burst size and delayed host lysis. Complementation of gp49 with HydH5 from bacteriophage vB_SauS-phiIPLA88 restored the wild-type phenotype.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Reference27 articles.

1. Peptidoglycan hydrolytic activities associated with bacteriophage virions;Moak;Mol. Microbiol.,2004

2. Bacteriophage virion-associated peptidoglycan hydrolases: potential new enzybiotics;Rodríguez-Rubio;Crit. Rev. Microbiol.,2012

3. Lysis from without;Abedon;Bacteriophage,2011

4. Role of the Gp16 lytic transglycosylase motif in bacteriophage T7 virions at the initiation of infection;Moak;Mol. Microbiol.,2000

5. Bacteriophage PRD1 DNA entry uses a viral membrane-associated transglycosylase activity;Rydman;Mol. Microbiol.,2000

Cited by 18 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Viral Proteins Involved in the Adsorption Process of Deep-Purple, a Siphovirus Infecting Members of the Bacillus cereus Group;Applied and Environmental Microbiology;2022-05-24

2. The Use of Bacteriophages in Biotechnology and Recent Insights into Proteomics;Antibiotics;2022-05-13

3. Predicting Bacteriophage Enzymes and Hydrolases by Using Combined Features;Frontiers in Bioengineering and Biotechnology;2020-03-24

4. Structure of the host cell recognition and penetration machinery of a Staphylococcus aureus bacteriophage;PLOS Pathogens;2020-02-18

5. Phage Therapy: An Alternative to Antibiotics;Biocommunication of Phages;2020