Nine-Year Surveillance of Methicillin-Resistant Staphylococcus aureus in a Hospital Suggests Instability of mecA DNA Region in an Epidemic Strain-Reference-Cited by-同舟云学术

Nine-Year Surveillance of Methicillin-Resistant Staphylococcus aureus in a Hospital Suggests Instability of mecA DNA Region in an Epidemic Strain

Published:2002-03 Issue:3 Volume:40 Page:1048-1052
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Donnio Pierre-Yves¹²,Louvet Laurence¹,Preney Laure¹,Nicolas Denis¹,Avril Jean-Loup¹²,Desbordes Laurent¹²

Affiliation:

1. Laboratoire de Bactériologie-Virologie, Centre Hospitalier Universitaire

2. UPRES 12-54 Microbiologie, Université de Rennes 1, 35033 Rennes Cedex 9, France

Abstract

ABSTRACT The distributions of the antibiotic resistance patterns in a population of Staphylococcus aureus isolates from a teaching hospital were studied over a 9-year period. The results indicate the existence of successive major epidemic methicillin-resistant strains and the emergence of a methicillin-susceptible strain with an unusual resistance pattern. Our findings suggest that this methicillin-susceptible S . aureus strain could be derived from the dominant gentamicin-susceptible methicillin-resistant S . aureus strain with the loss of a 40-kb DNA fragment.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.40.3.1048-1052.2002

Reference23 articles.

1. Quantitative antibiogram typing using inhibition zone diameters compared with ribotyping for epidemiological typing of methicillin-resistant Staphylococcus aureus

2. Blanc, D. S., P. Francioli, A. Le Coustumier, L. Gazagne, E. Lecaillon, P. Gueudet, F. Vandenesch, and J. Etienne. 2001. Reemergence of gentamicin-susceptible strains of methicillin-resistant Staphylococcus aureus in France: a phylogenetic approach. J. Clin. Microbiol.139:2287-2290.

3. DNA polymorphisms in methicillin-susceptible and methicillin-resistant strains of Staphylococcus aureus

4. Deplano, A., P. T. Tassios, Y. Glupczynski, E. Godfroid, and M. J. Struelens. 2000. In vivo deletion of the methicillin resistance mec region from the chromosome of Staphylococcus aureus strains. J. Antimicrob. Chemother.46:617-619.

5. Intercontinental Spread of a Multidrug-Resistant MethicillinResistant Staphylococcus aureus Clone

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