Successful Outcome of Treatment of a Disseminated Infection Due to Fusarium dimerum in a Leukemia Patient-Reference-Cited by-同舟云学术

Successful Outcome of Treatment of a Disseminated Infection Due to Fusarium dimerum in a Leukemia Patient

Published:2002-03 Issue:3 Volume:40 Page:1100-1102
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Letscher-Bru Valérie¹,Campos France²,Waller Jocelyn¹,Randriamahazaka Raoul²,Candolfi Ermanno¹,Herbrecht Raoul²

Affiliation:

1. Institut de Parasitologie et de Pathologie Tropicale, Faculté de Médecine, 67000 Strasbourg

2. Département d'Hématologie et d'Oncologie, Hôpital de Hautepierre, 67098 Strasbourg, France

Abstract

ABSTRACT We report the first case of proven disseminated infection due to Fusarium dimerum associated with a favorable outcome in a patient with acute leukemia and prolonged neutropenia. The patient presented persistent fever, multiple necrotic skin lesions, and bilateral pneumopathy. F. dimerum was first isolated from three blood cultures and then from a skin biopsy and a mouth wash. Microscopy of positive blood cultures showed hyphae with phialides and few curved unicellular and some rare bicellular phialoconidia, permitting immediate presumptive identification of the genus Fusarium . The patient failed to respond to conventional amphotericin B but recovered after treatment was switched to amphotericin B-lipid complex and neutrophil recovery.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.40.3.1100-1102.2002

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