Affiliation:
1. Departments of Pediatrics, Cedars of Lebanon Hospital, Division of Cedars-Sinai Hospital, and the University of California Center for Health Sciences, Los Angeles, California
Abstract
Kagan
, B. M. (Cedars of Lebanon Hospital, Los Angeles, Calif.),
Susan Zolla, R. Busser, and Silvija Liepnieks
. Sensitivity of coccal and L forms of
Staphylococcus aureus
to five antibiotics. J. Bacteriol.
88:
630–632. 1964.—Antibiotics whose primary site of action is in the cell wall (penicillin and cephalothin) do not inhibit growth of L-phase organisms. In this study, kanamycin, neomycin, polymyxin B, lincomycin, and gentamycin were found to be more active against L-phase growth of
Staphylococcus aureus
in vitro than against the coccal forms. Therefore, their primary site of antimicrobial activity appears to be other than that involved in the synthesis or integrity of the cell wall.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Reference11 articles.
1. In vitro biological activity of cephalothin;CHANG T.-W.;J. Bacteriol.,1963
2. DAVIS B. D. AND D. S. FEINGOLD. 1962. Antimicrobial agents: mechanism of action and use in metabolic studies. In J. C. Gunsalus and R. Y. Stanier [ed.] The bacteria vol. 4 p. 343-397. Academic Press Inc. New York.
3. The absorption of polymyxin E by bacteria and bacterial cell walls and its bactericidal action;FEW A. V.;J. Gen. Microbiol.,1953
4. Induction and cultivation of staphylococcal L forms in the presence of methicillin;KAGAN B. M.;J. Bacteriol.,1962
5. MASON D. J. A. DIETZ AND C. DEBOER. 1963. Lincomycin a new antibiotic. I. Discovery and biological properties. Antimicrobial Agents and Chemotherapy-1962 p. 554-559.
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