Affiliation:
1. Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts 02115
Abstract
ABSTRACT
The
Staphylococcus aureus cap5P
and
cap5O
genes of the type 5 capsule biosynthetic locus restore enterobacterial common-antigen expression to
Escherichia coli
mutants defective in
rffE
and
rffD
gene expression, respectively. Cap5P and Cap5O likely function as UDP-GlcNAc 2-epimerase and UDP-ManNAc dehydrogenase enzymes, respectively, in the synthesis of the capsule precursor UDP-ManNAcA.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Cited by
15 articles.
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