High Frequency of Mutator Strains among Human Uropathogenic Escherichia coli Isolates

Author:

Denamur Erick1,Bonacorsi Stéphane2,Giraud Antoine3,Duriez Patrick13,Hilali Farida4,Amorin Christine1,Bingen Edouard2,Andremont Antoine4,Picard Bertrand5,Taddei François3,Matic Ivan3

Affiliation:

1. INSERM U 458

2. Laboratoire d’Étude de Génétique Bactérienne dans les Infections de l’Enfant (EA3105)

3. Hôpital Robert Debré, INSERM EPI 9916, Faculté de Médecine Necker-Enfants Malades, Université René Descartes—Paris V

4. INSERM EPI 9933, Hôpital Bichat-Claude Bernard, AP-HP, Paris

5. Laboratoire de Microbiologie, Hôpital Morvan, Brest, France

Abstract

ABSTRACT By using a panel of 603 commensal and pathogenic Escherichia coli and Shigella isolates, we showed that mutation rates of strains vary considerably among different ecotypes. Uropathogenic strains had the highest frequency of mutators, while strains from patients with bacteremia had the lowest mutation rates. No correlation between the mutation rates and antibiotic resistance was observed among the studied strains.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3