Affiliation:
1. Department of Microbiology, Faculty of Pharmaceutical Sciences, Okayama University, Tsushima, Okayama 700-8530, Japan
Abstract
ABSTRACT
Gene
vmrA
, cloned from
Vibrio parahaemolyticus
, made
Escherichia coli
resistant to 4prime;,6-diamino-2-phenylindol, tetraphenylphosphonium chloride, acriflavine, and ethidium bromide. VmrA belongs to the DinF branch of MATE family efflux transporters. VmrA catalyzed acriflavine efflux and showed Na
+
/drug transporter activity because the addition of tetraphenylphosphonium to Na
+
-loaded cells caused Na
+
efflux.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
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