Affiliation:
1. Department of Biology, School of Science, Osaka University, Osaka, Japan
Abstract
Sugino, Yoshinobu
(Osaka University, Osaka, Japan)
and Yukinori Hirota
. Conjugal fertility associated with resistance factor R in
Escherichia coli
. J. Bacteriol.
84:
902–910. 1962.—The introduction of the contagious drug-resistance factor, R, into an F
−
strain of
Escherichia coli
allows the R
+
F
−
strain to mate with F
−
R
−
strains. The chromosome fragment transferred from the R
+
cell is relatively large, comparable to the conjugation between F
+
or Hfr male and F
−
female bacteria. The complex R factor has been analyzed by transduction with phage Pl. Within the R factor, the fertility determinant is inseparable from the determinant responsible for its infectivity, but can be separated from the loci for drug resistance. R thus resembles the category of complex F factors (F-primes) previously analyzed.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
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