Stabilities of Dried Suspensions of Influenza Virus Sealed in a Vacuum or Under Different Gases-Reference-Cited by-同舟云学术

Stabilities of Dried Suspensions of Influenza Virus Sealed in a Vacuum or Under Different Gases

Published:1969-06 Issue:6 Volume:17 Page:830-835
ISSN:0003-6919
Container-title:Applied Microbiology
language:en
Short-container-title:Appl Microbiol

Author:

Greiff Donald¹²³,Rightsel Wilton A.¹²³

Affiliation:

1. Department of Pathology, Marquette School of Medicine, Inc., Milwauke, Wisconsin 53233

2. Department of Pathology, Baptist Memorial Hospital, Memphis, Tennessee 38103

3. Department of Microbiology, University of Tennessee School of Basic Medical Sciences, Memphis, Tennessee 38103

Abstract

Suspensions of purified influenza virus, dried to a 1.4% content of residual moisture by sublimation of ice in vacuo, were sealed in a vacuum or under different gases of high purity. The stabilities of the several preparations were determined by an accelerated storage test. Based on the times predicted for the dried preparations stored at different temperatures to lose 1 log of infectivity titer, the order of stabilities in relation to sealing in vacuum or under different gases was as follows: helium > hydrogen > vacuum > argon > nitrogen > oxygen > carbon dioxide.

Publisher

American Society for Microbiology

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

https://journals.asm.org/doi/pdf/10.1128/am.17.6.830-835.1969

Reference21 articles.

1. Preservation of microorganisms by freeze-drying. II. The destructive action of oxygen. Additional stabilizers for Serratia marcescens. Experiments with other microorganisms;Benedict R. G.;Appl. Microbiol.,1961

2. Collier L. H. 1954. A discussion on the maintenance of cultures by freeze-drying p. 41. H. M. Stationery Office London.

3. Dushman S. 1962. Kinetic theory of gases p. 1-79. In J. M. Lafferty (ed.) Scientific foundations of vacuum technique 2nd ed. John Wiley & Sons Inc. New York.

4. The application of the theory of absolute reaction rates to proteins;Eyring H.;Chem. Rev.,1939

5. Greiff D. 1960. The effects of freezing low temperature storage and drying by vacuum sublimation on the activities of viruses and cellular particulates p. 167-187. In A. S. Parkes and A. U. Smith (ed.) Recent research in freezing and drying. Charles C Thomas Publisher Springfield Ill.

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Influence of residual moisture and sealing atmosphere on viability of two freeze-dried viral vaccines;Journal of Clinical Microbiology;1980-10

2. Effects of Various Gases on the Survival of Dried Bacteria During Storage;Applied Microbiology;1973-08

3. Stabilities of Suspensions of Influenza Virus Dried by Sublimation of Ice In Vacuo to Different Contents of Residual Moisture and Sealed Under Different Gases;Applied Microbiology;1970-12