Propagation of MM Virus in L Cells-Reference-Cited by-同舟云学术

Propagation of MM Virus in L Cells

Published:1969-06 Issue:6 Volume:17 Page:811-814
ISSN:0003-6919
Container-title:Applied Microbiology
language:en
Short-container-title:Appl Microbiol

Author:

Giron D. J.¹,Pindak F. F.¹

Affiliation:

1. Biosciences Division, Infectious Diseases Branch, USAF School of Aerospace Medicine, Brooks Air Force Base, Texas 78235

Abstract

MM virus (mouse-brain stock) replicated to a limited extent in L cells without cytopathic effects; the average yield was less than 1 plaque-forming unit/cell. Passage in BHK-21 cells resulted in MM virus [MM(BHK)] which replicated to high titers (200 to 300 plaque-forming units/cell) in L cells with complete cytopathic effects. Appearance of mature MM(BHK) virus in L-cell cultures begins 4 hr after infection and is completed by 8 hr. Release of mature virus was slow (less than 1% at 8 hr) but was completed by 24 hr.

Publisher

American Society for Microbiology

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

https://journals.asm.org/doi/pdf/10.1128/am.17.6.811-814.1969

Reference8 articles.

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