Risk Factors for Isolation of Strains Susceptible Only to Polymyxin among Patients with Pseudomonas aeruginosa Bacteremia-Reference-Cited by-同舟云学术

Risk Factors for Isolation of Strains Susceptible Only to Polymyxin among Patients with Pseudomonas aeruginosa Bacteremia

Published:2006-07 Issue:7 Volume:50 Page:2541-2543
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Falagas Matthew E.¹²³,Koletsi Patra K.¹,Kopterides Petros¹⁴,Michalopoulos Argyris¹⁵

Affiliation:

1. Alfa Institute of Biomedical Sciences, Athens, Greece

2. Department of Medicine, Henry Dunant Hospital, Athens, Greece

3. Department of Medicine, Tufts University School of Medicine, Boston, Massachusetts

4. Critical Care Department, Attikon University Hospital, Athens, Greece

5. Intensive Care Unit, Henry Dunant Hospital, Athens, Greece

Abstract

ABSTRACT We conducted a case-control study to identify risk factors associated with the isolation of Pseudomonas aeruginosa strains susceptible only to polymyxin from blood by comparing data between 16 patients with blood isolates that were susceptible only to polymyxins and 40 patients with blood isolates that were susceptible to carbapenems. The multivariable analysis showed that exposure to carbapenems was associated with the development of P. aeruginosa bacteremia susceptible only to polymyxin (odds ratio, 9.0; 95% confidence interval, 2.4 to 34.3; P = 0.001).

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00224-06

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