Author:
Jovcic Branko,Lepsanovic Zorica,Suljagic Vesna,Rackov Gorjana,Begovic Jelena,Topisirovic Ljubisa,Kojic Milan
Abstract
ABSTRACTThis work reports, for the first time, the presence of New Delhi metallo-β-lactamase 1 (NDM-1) inPseudomonas aeruginosa. Moreover, this is the first report of the NDM-1 presence in the Balkan region. Cosmid gene libraries of carbapenem-nonsusceptiblePseudomonas aeruginosaclinical isolates MMA83 and MMA533 were screened for the presence of metallo-β-lactamases. Accordingly, both MMA83 and MMA533 carried theblaNDM-1gene. Pulsed-field gel electrophoresis (PFGE) analysis indicated that strains MMA83 and MMA533 belonged to different clonal groups. Five additional isolates from different patients clonally related to either MMA83 or MMA533 were found to be NDM-1 positive.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
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