Abstract
Replication of coxsackievirus B3 occurred for days in cultures of murine neonatal skin fibroblasts in the absence of cytopathology and resulted in alteration of the plasma membrane. Dual immunofluorescence studies showed that the lectin Ulex europaeus agglutinin I bound only to cells producing viral capsid antigens. Cultures of coxsackievirus B3-inoculated murine neonatal skin fibroblasts showed maximum binding of this lectin at 72 h postinoculation. These data show that in a nonlytic infection a picornavirus can alter the surface of an infected cell.
Publisher
American Society for Microbiology
Subject
Virology,Insect Science,Immunology,Microbiology
Reference24 articles.
1. The role of viruses in the production of heart disease;Burch G. E.;Am. J. Cardiol.,1972
2. Burns W. H. and A. C. Allison. 1977. Surface antigens of virus-infected cells p. 211-247. In G. Poste and G. L. Nicolson (ed.) Virus infection and the cell surface. North-Holland Publishing Co. New York.
3. Crowell R. L. and B. J. Landau. 1979. Picornaviridae: enteroviruses-coxsackieviruses. p. 131-155. In G. D. Hsuing and R. Green (ed.) CRC handbook series in clinical laboratory science virology and rickettsiology. vol. 1. part 1. CRC Press. Inc. Boca Raton Fla.
4. Characterization and myocarditic capabilities of coxsackievirus B3 variants in selected mouse strains;Gauntt C. J.;J. Virol.,1984
5. Temperature-sensitive mutant of coxsackievirus B3 establishes resistance in neonatal mice that protects them during adolescence against coxsackievirus B3-induced myocarditis;Gauntt C. J.;Infect. Immun.,1983
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