The pH Robustness of Bacterial Sensing-Reference-Cited by-同舟云学术

The pH Robustness of Bacterial Sensing

Published:2022-10-26 Issue:5 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Monteagudo-Cascales Elizabet¹^ORCID,Martín-Mora David¹^ORCID,Xu Wenhao²,Sourjik Victor²^ORCID,Matilla Miguel A.¹^ORCID,Ortega Álvaro³^ORCID,Krell Tino¹^ORCID

Affiliation:

1. Department of Environmental Protection, Estación Experimental del Zaidín, Consejo Superior de Investigaciones Científicas, Granada, Spain

2. Max Planck Institute for Terrestrial Microbiology and Center for Synthetic Microbiology (SYNMIKRO), Marburg, Germany

3. Department of Biochemistry and Molecular Biology ‘B’ and Immunology, Faculty of Chemistry, University of Murcia, Regional Campus of International Excellence “Campus Mare Nostrum”, Murcia, Spain

Abstract

Demonstration of the pH robustness of extracytoplasmic sensing reveals a previously undescribed evolutionary mechanism that enables bacteria to monitor environmental changes under changing conditions. This mechanism includes the maintenance of the dimeric state of four-helixbundle ligand-binding domains (LBDs).

Funder

Ministerio de Ciencia e Innovación

Consejería de Conocimiento, Investigación y Universidad, Junta de Andalucía

EC | European Regional Development Fund

Seneca Foundation CARM

Hessian Ministry of Higher Education, Research and Arts

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.01650-22