Affiliation:
1. Guangdong Provincial Key Laboratory of New Drug Screening, Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China
2. School of Medicine, Jinan University, Guangzhou, China
Abstract
HIV-1 latency is systematically modulated by host factors and viral proteins. In our work, we identified a critical role of host factor ubiquitin-like with PHD and RING finger domain 1 (UHRF1) in HIV-1 latency via the modulation of the viral protein Tat stability.
Funder
National Natural Science Foundation of China
Natural Science Foundation of Guangdong Province
Guangdong Basic and Applied Basic Research Foundation
Opening Project of Zhejiang Provincial Preponderant and Characteristic Subject of Key University (Traditional Chinese Pharmacology) at Zhejiang Chinese Medical University
Guangdong Basic and Applied Basic Rsearch Foundation
Guangzhou Science and Technology Basis and Applied Basic Research Foundation
Publisher
American Society for Microbiology
Cited by
9 articles.
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