Lack of relevance of kinetic parameters for exocellular DD-peptidases to cephalosporin MICs-Reference-Cited by-同舟云学术

Lack of relevance of kinetic parameters for exocellular DD-peptidases to cephalosporin MICs

Published:1986-05 Issue:5 Volume:29 Page:774-780
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Boyd D B,Ott J L

Abstract

MICs of a set of cephalosporins against a variety of gram-positive and gram-negative pathogens showed no strong correlations with the rate at which these inhibitors acylate or are deacylated by beta-lactam-sensitive DD-peptidases excreted by Streptomyces sp. strain R61 and Actinomadura sp. strain R39.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.29.5.774

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