Pharmacokinetic study of lenampicillin (KBT-1585) in healthy volunteers-Reference-Cited by-同舟云学术

Pharmacokinetic study of lenampicillin (KBT-1585) in healthy volunteers

Published:1986-05 Issue:5 Volume:29 Page:948-950
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Saito A,Nakashima M

Abstract

The pharmacokinetic properties of lenampicillin (KBT-1585), a new ampicillin ester, were investigated in 41 healthy volunteers. The maximum concentration of ampicillin in serum after oral administration of 400 mg of lenampicillin was 6.5 micrograms/ml at 0.70 h, and that after a equimolar dosage of ampicillin was 2.9 micrograms/ml at 0.87 h.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.29.5.948

Reference26 articles.

1. .87 - 0.22 10.8 - 1.8 0.61 - 0.26 48.1 - 5.3

2. .80 - 0.22 19.7 - 6.2 0.83 - 0.07 49.5 - 13.7

3. .27 - 0.41 9.3 + 3.0 0.67 - 0.15 42.2 - 3.3

4. .09 - 0.34 9.0 - 4.4 0.70 - 0.09 41.7 - 4.0

5. .58 - 0.13 9.6 - 1.7 0.68 - 0.09 53.2 - 6.2

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