Affiliation:
1. Department of Medicine, Medical College of Pennsylvania, Philadelphia 19129.
Abstract
This study compared difloxacin administered orally, enoxacin administered orally, and cefazolin administered intramuscularly for the treatment of experimental Staphylococcus aureus endocarditis. Difloxacin significantly reduced bacterial counts of vegetations compared with enoxacin. This study demonstrated that difloxacin was significantly more effective than enoxacin and as effective as cefazolin for the treatment of S. aureus endocarditis in rabbits.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Reference11 articles.
1. Anhalt J. P. 1985. Assays for antimicrobial agents in body fluids p. 1009-1014. In E. H. Lennette A. Balows W. J. Hausler Jr. and H. J. Shadomy (ed.) Manual of clinical microbiology 4th ed. American Society for Microbiology Washington D.C.
2. Efficacy of ciprofloxacin for experimental endocarditis caused by methicillin-susceptible or -resistant strains of Staphylococcus aureus;Carpenter T. C.;Antimicrob. Agents Chemother.,1986
3. Antibiotic synergism in enterococcal endocarditis;Carrizosa J.;J. Lab. Clin. Med.,1976
4. Chemotherapy of experimental streptococcal endocarditis. I. Comparison of commonly recommended prophylactic regimens;Durack D. T.;J. Clin. Invest.,1973
5. Enoxacin compared with vancomycin for the treatment of experimental methicillin-resistant Staphylococcus aureus endocarditis;Gilbert M.;Antimicrob. Agents Chemother.,1986
Cited by
7 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献