Peste des Petits Ruminants Virus-Induced Novel MicroRNA miR-3 Contributes To Inhibit Type I IFN Production by Targeting IRAK1

Author:

Li Huan1,Xue Qinghong2,Wan Yangli1,Chen Yan1,Zeng Wei1,Wei Shaopeng1,Zhang Yanming1,Wang Jingyu1,Qi Xuefeng1ORCID

Affiliation:

1. College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China

2. China Institute of Veterinary Drug Control, Beijing, China

Abstract

Peste des petits ruminants virus (PPRV) induces in the host a transient but severe immunosuppression, which threatens both small livestock and endangered susceptible wildlife populations in many countries. Despite extensive research, the mechanism underlying PPRV immune system evasion remains elusive.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

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