The Edwardsiella piscicida Type III Effector EseJ Suppresses Expression of Type 1 Fimbriae, Leading to Decreased Bacterial Adherence to Host Cells-Reference-Cited by-同舟云学术

The Edwardsiella piscicida Type III Effector EseJ Suppresses Expression of Type 1 Fimbriae, Leading to Decreased Bacterial Adherence to Host Cells

Published:2019-07 Issue:7 Volume:87 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Zhang Qian¹²³,He Tian Tian¹²³,Li Duan You¹²³,Liu Lu Yi¹²,Nie Pin¹²⁴⁵,Xie Hai Xia¹²

Affiliation:

1. State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China

2. Key Laboratory of Aquaculture Diseases Control, Ministry of Agriculture, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China

3. University of Chinese Academy of Sciences, Beijing, China

4. Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, Shandong Province, China

5. College of Marine Science and Engineering, Qingdao Agricultural University, Qingdao, Shandong Province, China

Abstract

The type III secretion system (T3SS) of Edwardsiella piscicida plays a crucial role in its pathogenesis. Our previous study indicated that the T3SS effector protein EseJ inhibits the bacterium’s adhesion to epithelioma papillosum cyprini (EPC) cells, while the mechanism of the inhibition remains elusive.

Funder

China Agriculture Research System

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.00187-19

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