Affiliation:
1. Division of Geographic Medicine and Infectious Diseases, New England Medical Center, Boston, Massachusetts 02111
Abstract
ABSTRACT
Vibrio cholerae
is a versatile bacterium that flourishes in diverse environments, including the human intestine, rivers, lakes, estuaries, and the ocean. Surface attachment is believed to be essential for colonization of all of these natural environments. Previous studies have demonstrated that the
vps
genes, which encode proteins required for exopolysaccharide synthesis and transport, are required for
V. cholerae
biofilm development in Luria-Bertani broth. In this work, we showed that
V. cholerae
forms
vps
-dependent biofilms and
vps-
independent biofilms. The
vps
-dependent and -independent biofilms differ in their environmental activators and in architecture. Our results suggest that environmental activators of
vps
-dependent biofilm development are present in freshwater, while environmental activators of
vps
-independent biofilm development are present in seawater. The distinct environmental requirements for the two modes of biofilm development suggest that
vps-
dependent biofilm development and
vps-
independent biofilm development may play distinct roles in the natural environment.
Publisher
American Society for Microbiology
Subject
Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology
Cited by
123 articles.
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