Affiliation:
1. Institute of Microbiology, University of Bologna, 40126 Bologna, Italy
Abstract
Evidence is presented that lysolecithin is involved in the fusing and hemolytic activities of Sendai virus. Treatment of the virus with phospholipase B (lysolecithinase) specifically inactivates the hemolytic and fusing abilities, without affecting the infectivity and the capability of the virus to hemagglutinate and adsorb to cells. The possible identity of lysolecithin with the “cell fusion factor” of paramyxoviruses and the mechanism of cell fusion are discussed.
Publisher
American Society for Microbiology
Subject
Virology,Insect Science,Immunology,Microbiology
Reference10 articles.
1. Presence of two different virall agents in braiin cells of patients with subacute sclerosing panencephalitis;Barbanti-Brodalno G.;Proc. Soc. Exp. Biol. Med.,1970
2. The lipids of paramyxoviruscs: a comparative study of Sendai zind Newcastle disease viruses;Blough H. A.;Virology,1968
3. Metabolism of lecithin aind virus-induced cell fusion;Elsbach P.;Proc. Soc. Exp. Biol. Med.,1969
4. Studies on Sendai virus cell fusion factor;Guggenheim M. A.;Proc. Soc. Exp. Biol. Med.,1968
5. Hosaka Y. 1970. Early cell fusioni by sonicated H.V.J. p. 684-696. In R. D. Barry and B. W. J. Mahy (ed.) The biology of large RNA viruses. Academic Press Inc. New York.
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