A Nosocomial Cluster of Candida inconspicua Infections in Patients with Hematological Malignancies-Reference-Cited by-同舟云学术

A Nosocomial Cluster of Candida inconspicua Infections in Patients with Hematological Malignancies

Published:1998-03 Issue:3 Volume:36 Page:792-795
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

D’Antonio Domenico¹²,Violante Beatrice¹²,Mazzoni Aldo³,Bonfini Tiziana²,Capuani M. Assunta⁴,D’Aloia Francesco⁴,Iacone Antonio¹²,Schioppa Francesco⁴,Romano Ferdinando⁴

Affiliation:

1. Servizio di Microbiologia Clinica del Dipartimento di Ematologia ed Oncologia, Ospedale Santo Spirito, Pescara,1

2. Cattedra di Ematologia2 and

3. Istituto di Microbiologia, Università di Bologna, Bologna,3 Italy

4. Sezione di Epidemiologia e Sanità Pubblica, Dipartimento di Scienze Biomediche,4 Università G. D’Annunzio, Chieti, and

Abstract

ABSTRACT Candida inconspicua was recovered from three patients with hematological malignancies. Two patients had intravenous-catheter-associated fungemia, whereas the third had fungal hepatitis. The three cases of infection occurred over a period of 1 month in patients staying in adjacent single rooms. In vitro susceptibility testing of fungal strains showed all isolates to be resistant to fluconazole, with MICs greater than 32 μg/ml. All of the strains had identical DNA restriction profiles and randomly amplified polymorphic DNA fingerprints. These data suggest a nosocomially acquired infection emanating from a common source within the hospital environment.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.36.3.792-795.1998

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