Ampicillin-resistant enterococcal species in an acute-care hospital

Author:

Oster S E1,Chirurgi V A1,Goldberg A A1,Aiken S1,McCabe R E1

Affiliation:

1. Medical Service, Veterans Administration Medical Center, Martinez, California 94553.

Abstract

A prospective review of all enterococcal isolates for 13 months showed that 9.0% were resistant to ampicillin (MIC, greater than or equal to 16 micrograms/ml; zone diameter, less than 15 mm), as determined by the Vitek system, disk diffusion, microdilution MIC testing, and macrodilution MIC testing. All were beta-lactamase negative. A total of 19 and 3 resistant isolates were from urine and intravascular sites, respectively. Ampicillin-resistant enterococci appear to be a growing clinical problem.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference15 articles.

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4. Transition from resistance to hypersusceptibility to betalactam antibiotics associated with loss of a low-affinity penicillin-binding protein in a Streptococcus faecium mutant highly resistant to penicillin;Fontana R.;Antimicrob. Agents Chemother.,1985

5. Jones R. W. A. L. Barry T. L. Gavan and J. A. Washington IH. 1985. Susceptibility tests: microdilution and macrodilution broth procedures p. 972-977. In E. H. Lennette A. Balows W. J. Hausler Jr. and H. J. Shadomy (ed.) Manual of clinical microbiology 4th ed. American Society for Microbiology Washington D.C.

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