Serum Antibody Response to Polysaccharides in Children with Recurrent Respiratory Tract Infections

Author:

López-Yap Alberto1,Abdelnour Arturo2,Lomonte Bruno3,Porras Oscar2

Affiliation:

1. Laboratorio Clı́nico, Caja de Seguro Social de Panamá,1

2. Servicio de Inmunologı́a, Hospital Nacional de Niños “Dr. Carlos Sáenz Herrera,”2 and

3. Instituto Clodomiro Picado, Facultad de Microbiologı́a, Universidad de Costa Rica,3 San José, Costa Rica

Abstract

ABSTRACT We evaluated children (15-months old and older) with recurrent upper respiratory tract infections and normal levels of immunoglobulins in serum for specific polysaccharide immunodeficiency using an enzyme-linked immunosorbent assay method. Results showed that of 12 patients vaccinated with Act-HIB vaccine, one did not develop specific antibodies to Haemophilus influenzae type b, demonstrating that such immunodeficiency is present in Costa Rican children.

Publisher

American Society for Microbiology

Subject

Microbiology (medical),Clinical Biochemistry,Immunology,Immunology and Allergy

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