Affiliation:
1. Department of Molecular Genetics and Virology, Weizmann Institute of Science, Rehovot, Israel.
Abstract
The hepatitis B virus enhancer can be dissected into multiple functional elements, one of which is the E element. We show here that the E element binds multiple nuclear proteins that are essential for its enhancer activity. These findings, together with the ability of this element to respond to at least two different viral transactivators, suggest that the E element is an enhancer modulator capable of binding different factors and responding to multiple stimuli.
Publisher
American Society for Microbiology
Subject
Virology,Insect Science,Immunology,Microbiology
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