Molecular Patchwork: Chromosomal Recombination between Two Helicobacter pylori Strains during Natural Colonization-Reference-Cited by-同舟云学术

Molecular Patchwork: Chromosomal Recombination between Two Helicobacter pylori Strains during Natural Colonization

Published:2003-05 Issue:5 Volume:71 Page:2907-2910
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Smeets Leonard C.¹,Arents Nicolaas L. A.²,van Zwet Anton A.²,Vandenbroucke-Grauls Christina M. J. E.¹,Verboom Theo¹,Bitter Wilbert¹,Kusters Johannes G.¹³

Affiliation:

1. Department of Medical Microbiology and Infection Control, Vrije Universiteit Medical Center, Amsterdam

2. Department of Medical Microbiology, Bethesda Hospital, Hoogeveen

3. Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, The Netherlands

Abstract

ABSTRACT Genetic analysis of two Helicobacter pylori strains isolated from a single gastric biopsy showed evidence of extensive horizontal gene transfer. Several large recombinations were identified in the rdxA gene, which is involved in metronidazole resistance.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.71.5.2907-2910.2003

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