PLC/PRF/5 (Alexander) hepatoma cell line: further characterization and studies of infectivity-Reference-Cited by-同舟云学术

PLC/PRF/5 (Alexander) hepatoma cell line: further characterization and studies of infectivity

Published:1980-11 Issue:2 Volume:30 Page:607-611
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Daemer R J,Feinstone S M,Alexander J J,Tully J G,London W T,Wong D C,Purcell R H

Abstract

The Alexander hepatoma cell line, PLC/PRF/5, was studied for evidence of hepatitis B virus markers and alpha-fetoprotein. Only hepatitis B surface antigen and alpha-fetoprotein were detected. Induction experiments with 5-iodo-2'-deoxyuridine and inoculation of chimpanzees with whole cells or tissue culture fluid did not reveal evidence of synthesis of additional hepatitis B virus markers or of production of infectious virus.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.30.2.607-611.1980

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